Dissertation/Thesis Abstract

The effect of using a powered toothbrush on MCP-1 and RANTES levels in patients with gingivitis
by Paquette, Linda L., M.S., The University of North Carolina at Chapel Hill, 2008, 42; 1454959
Abstract (Summary)

This pilot study investigated if a powered toothbrush significantly reduced the concentration of MCP-1 and RANTES over time in a gingivitis population, when compared to a manual toothbrush. Twenty gingivitis patients, 18-65 years of age with pocket depths ≤6mm and a minimum of 10% bleeding upon probing were enrolled. Participants were seen for 5 study visits and gingival crevicular fluid samples were collected at baseline and 24 weeks. With the exception of race (p=0.01), no statistically significant differences were found between the groups at baseline in clinical measurements, GCF levels of MCP-1 and RANTES and demographics. When comparing the treatment group to the control, no statistical differences were found between the GCF levels for MCP-1 and RANTES at baseline and 24 weeks post treatment (p=0.20 and p=0.19, respectively). Additional large sample studies are needed to determine if these findings can be confirmed.

Indexing (document details)
Advisor: Jared, Heather L., Wilder, Rebecca S., Barros, Silvana P.
School: The University of North Carolina at Chapel Hill
Department: Dentistry: Dental Hygiene
School Location: United States -- North Carolina
Source: MAI 46/06M, Masters Abstracts International
Subjects: Dental care
Keywords: GCF levels, Gingivitis, MCP-1, Powered toothbrush, RANTES
Publication Number: 1454959
ISBN: 978-0-549-57491-0
Copyright © 2020 ProQuest LLC. All rights reserved. Terms and Conditions Privacy Policy Cookie Policy