Latent Autoimmune Diabetes in Adults (LADA) is an ill-defined autoimmune disorder separated from typical type 1 diabetes (DM-1), because of features suggestive of type 2 diabetes (DM-2). To better understand LADA, we compared it with ketosis prone type 2 diabetes (KPDM-2)—another ‘mixed’ diabetes form of DM-2 with features of DM-1. We measured clinical and biochemical criteria used in the definition of metabolic syndrome to test the degree of similarity of LADA and KPDM-2 to DM-2. LADA was leaner with fewer metabolic syndrome characteristics than KPDM-2, suggesting that LADA resembles DM-1 and KPDM-2 resembles DM-2, despite suggestion of overlap. We conclude that ‘type 2-like’ features of LADA are likely due to age, with little difference between LADA and type 1 diabetes. LADA patients should be treated like all other autoimmune diabetes patients, with early screening to enable diagnosis and early insulin therapy that might prevent lifelong complications of diabetes.
|School:||California State University, Long Beach|
|School Location:||United States -- California|
|Source:||MAI 49/05M, Masters Abstracts International|
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