Cystic fibrosis (CF) is a genetic disorder that affects the exocrine glands. CF patients are at risk for fat-soluble vitamin deficiencies. Chronic infections and inflammation damages the lungs. Vitamin A affects the immune system and vitamin E is an antioxidant, therefore both may be protective. The purpose of this study was to investigate the relationship between serum vitamin A and E levels and markers of lung function. The secondary purpose was to investigate the impact of serum vitamin A and E levels on markers of lung function.
The results showed that serum vitamin A levels have a significant, weak positive relationship with forced expiratory volume (FEVI). Serum vitamin A levels and number of CF exacerbations did not have a significant relationship. Serum vitamin E levels were not significant with either marker of lung function. More research is needed to determine the optimal level of vitamin A for lung function.
|School:||California State University, Long Beach|
|School Location:||United States -- California|
|Source:||MAI 49/01M, Masters Abstracts International|
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