Dissertation/Thesis Abstract

Examination of novel loci to enhance paternal lineage relationship analysis
by Evans, Laura, M.S., University of North Texas Health Science Center at Fort Worth, 2010, 26; 1475881
Abstract (Summary)

Deoxyribonucleic acid (DNA) from 41 buccal swabs containing saliva and 7 punches containing blood was obtained from a Native American Alaskan population. Allele frequencies, observed and expected heterozygosities, p-values from the Fisher Exact Test, power of discrimination (PD), power of exclusion (PE), and mean power of exclusion (MPE) for each locus were determined for the 48 Native Alaskan samples amplified with the PowerPlex? 16 HS System. All loci except for D13S317 yielded p-values > 0.05, and thus failed to detect any departure from Hardy Weinberg Equilibrium (HWE). Haplotype distributions were determined for the 48 Native Alaskan samples amplified with the AmpFlSTR? Yfiler PCR Amplification Kit. There were a total of 36 different haplotypes observed among 48 individuals. The haplotype diversity value was 0.989.

Indexing (document details)
Advisor: Planz, John V.
Commitee: Budowle, Bruce, Siede, Wolfram
School: University of North Texas Health Science Center at Fort Worth
Department: Forensic Genetics
School Location: United States -- Texas
Source: MAI 48/05M, Masters Abstracts International
Source Type: DISSERTATION
Subjects: Genetics
Keywords: Alaska Native population, AmpFlSTR Cofiler PCR amplification kit, Haplotype diversity, Powerplex(RTM) 16 HS system, Short tandem repeats (STRs), Y-STRs
Publication Number: 1475881
ISBN: 9781109758443
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