Dissertation/Thesis Abstract

Development of a clinical research protocol to examine potential signals of insulin secretion in the presence of insulin resistance
by Centanni, Carrie H., M.S., California State University, Long Beach, 2009, 77; 1481776
Abstract (Summary)

The purpose of this project was to develop a clinical research protocol for a study to examine potential signals for insulin secretion in the presence of nicotinic acid-induced insulin resistance. All aspects of creating a research protocol were reviewed including study design, participant selection and study procedures. Clinical research regulations, ethical considerations and obtaining approval to conduct research were also covered.

The result of this project was the development of a clinical research protocol for an outpatient study to examine the effects of nicotinic acid-induced insulin resistance on insulin resistance, insulin secretion and the possible role of plasma interleukin-6 and acylation-stimulating protein in maintaining glucose homeostasis in healthy adults. The research protocol was submitted to the appropriate review boards and permission to conduct the research study was granted. After one participant completed the study, necessary modifications to the protocol were identified and implemented.

Indexing (document details)
Advisor: Lee, Jacqueline
School: California State University, Long Beach
School Location: United States -- California
Source: MAI 48/04M, Masters Abstracts International
Subjects: Endocrinology, Nutrition
Publication Number: 1481776
ISBN: 978-1-109-66941-1
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