Dissertation/Thesis Abstract

Hydroxylated Polychlorinated Biphenyl metabolites in blood: A study of pregnant women and their newborns in the Lower Rio Grande Valley
by Oberman, Ceceilia Celeste, M.S.P.H., The Texas A&M University System Health Science Center, 2008, 53; 1457610
Abstract (Summary)

Hydroxylated Polychlorinated Biphenyls (OH-PCBs) are metabolites of Polychlorinated Biphenyls (PCBs), a class of ubiquitous environmental contaminants banned in the United States in the 1970s for their persistence in the environment and living organisms, and subsequent health effects. OH-PCBs are probable carcinogens, thyroid inhibitors, and can cause interference with neurological and behavioral development. People living in Brownsville, Texas in the Lower Rio Grande Valley are frequently exposed to substandard environmental quality, including pollution from Mexico, and are therefore vulnerable to a variety of health outcomes. A previous study of a group of mothers and infants living in Brownsville found low levels of PCBs in bloods. The present study investigated levels of OH-PCBs to further assess the significance of PCBs as contaminants of interest in the area. Though OH-PCBs levels were lower than expected, they were present in all blood samples, demonstrating transplacental transfer from mothers to infants. The results indicate that PCB exposure may no longer be of severe concern in this area. Further research into similar chemicals and additional health threats in the Lower Rio Grande Valley remains a high priority.

Indexing (document details)
Advisor: McDonald, Thomas J.
Commitee: Blakely, Craig H., Donnelly, Kirby C.
School: The Texas A&M University System Health Science Center
Department: Environment & Occupational
School Location: United States -- Texas
Source: MAI 47/02M, Masters Abstracts International
Subjects: Public health, Environmental science
Keywords: Colonias, Environmental health, Hydroxylated polychlorinated biphenyls, Persistent organic pollutants, Prenatal health, Transboundary
Publication Number: 1457610
ISBN: 978-0-549-87975-6
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