Positive and negative feedback loops are common regulatory elements in biological signaling systems. This thesis includes a comprehensive description of feedback loops in signaling systems and also details specific feedback systems and feedback motifs. These include the STIM2/Orail negative feedback module in Ca2+ signaling and the dual positive feedback motif.
|School Location:||United States -- California|
|Source:||DAI-B 69/05, Dissertation Abstracts International|
|Keywords:||Calcium, Calcium signaling, Feedback loops, STIM2, Signaling, Switch|
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