The clinical laboratory represents an environment of constant change in regulation, accreditation standards and technical advancements. Training methods for clinical laboratory scientist personnel must be capable of rapidly incorporating new information, efficiently disseminating the material and effectively transferring knowledge. Web-based training (WBT) is a desirable training model, but is historically known to require a longer development time, higher cost and less customization than paper-based methods.

This thesis examines the principles of Design for Six Sigma (DFSS) and applies these principles to the development of a web-based training tool intended for clinical laboratory personnel. The DFSS project framework is compared to the Analysis, Design, Development, Implementation and Evaluation (ADDIE) training design methodology to demonstrate integration. Analysis of DFSS as applied to WBT demonstrates that it is an effective and efficient process of translating customer needs and requirements into the design and development of a web-based training product.