Underrepresentation of Latinas in leadership positions is remarkable, and the correspondent literature is limited. This qualitative, grounded theory study explored the leadership development of 11 successful Latina business leaders in the United States. Inducted theory and a practical leadership model revealed 3 themes and 24 processes that explain the transformation of Latinas into influential leaders. The study revealed that Latinas prepare for leadership by breaking negative stereotypes, improving personal capabilities, adopting positive contributions from their Latino culture, and by building self-confidence. Latinas transform into leaders by making a choice, aligning their self-identity with role models, enhancing their support system, and maturing a mindset that is impervious to barriers and that will keep them motivated in difficult times. Parents, partners, family, mentors, and organizations influence positively and negatively the transformation of Latinas as leaders. Latina leaders become influential by performing outstandingly, leading at various levels, building social capital, and gaining visibility and recognition. Discussion of the findings includes Latina leadership styles and some consequences of their leadership. The study provides recommendations for Latinas, their parents and partners, mentors and educators, leaders, organizations, and society as well as suggestions for additional research.