Clinical trials enroll a disproportionately low number of minority study participants. This results in scientific, ethical, and economic issues for U.S. citizens. The purpose of this qualitative exploratory case study was to examine the attitudes and perceptions of minority clinical trial research participants enrolled in trials in the United States before 2020. The study contributed to this body of knowledge, as it remains a significant health concern today. The research questions asked why individuals enrolled, whether previous clinical trial perceptions influenced enrolment, what influenced participation, and whether their attitude about research influenced enrollment? How did trust, awareness, and willingness to participate impact enrollment? The overarching theoretical frameworks of Cultural Consensus and Social Learning Theories framed this research. Eleven experienced research candidates were conveniently sampled, using semi-structured interviewing, to identifying common themes through constant comparison analysis, and context analysis. The resulting themes included that minority clinical trial enrollees do so to treat or prevent disease in self, to advance science or humanity (altruistic reasons), and for financial incentives. Both previous positive medical exposure and prior knowledge of clinical trials influenced their decision to enroll. Results support prior literature that enrollment may be enhanced through improved relationships with health providers, and education about clinical trials. Clinical trial practitioners and leaders should consider the individual needs of potential study candidates, build on previous positive experiences with health professionals, enhance educational processes, acknowledge potential clinical trial participants previous perceptions about clinical trials, and embrace cultural consciousness through the assistance of experienced minority research participants
|Commitee:||Burrell, Darrell, Underdahl Hatfield , Sharon (Louise)|
|School:||University of Phoenix|
|Department:||School of Advanced Studies|
|School Location:||United States -- Arizona|
|Source:||DAI-A 82/8(E), Dissertation Abstracts International|
|Subjects:||Health sciences, Health care management, Pharmaceutical sciences, Ethnic studies, Public health|
|Keywords:||Clinical trial enrollment, Clinical trials, Enrollment in clinical trials, Minorities in research, Pharmaceutical research, U.S. citizens, United States, Clinical trail practitioners|
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