Purpose: Neurotrophins serve a fundamental role in neural survival, development, function and exercise-dependent synaptic plasticity. Although brain derived neurotrophic factor (BDNF) production decreases as we age, there is a vast amount of support for moderate to high level intensity exercise as a mediator for ramping up production. Limited research indicates light therapy (LT) treatment may also increase peripheral BDNF, leaving the effects of this treatment poorly understood. Establishing methods to maximize the release of BDNF is beneficial to augment cognitive effects. Therefore, the purpose is to evaluate the influence of LT and acute bouts of aerobic exercise (AE) on serum BDNF concentrations in adults over the age of 55.
Methods: A total of 6 participants (1 male, 5 female, 67 ± 4.10 years 171 ± 8.41 centimeters, 79.4 ± 6.75 kilograms) completed VO2 max testing and the following three exercise sessions separated by 48 hours: (1) 30 minute LT session, (2) 30 minute cycling session and (3) LT exposure during a 30 minute cycling session. Cycling sessions were completed at 65-75% of maximal heart rate as determined by VO2max, while maintaining 60rpms. Venous blood samples were collected pre and immediately post each condition for serum BDNF quantification.
Results: Mean serum BDNF concentrations were not statistically significantly increased between the three conditions or between the two time points. Cohen’s D values suggest small effect sizes for AE (d = 0.27, r = 0.13) and LT (d = 0.28, r = 0.14) conditions, with a very small effect size for the COMB (d = 0.06, r = 0.03) condition.
Conclusions: Aerobic exercise and light therapy may separately serve as interventions to increase serum BDNF levels. Combining the two treatments requires additional investigation to determine additive effects.
|Commitee:||Escobar, Kurt, Cotter, Joshua A.|
|School:||California State University, Long Beach|
|School Location:||United States -- California|
|Source:||MAI 82/4(E), Masters Abstracts International|
|Subjects:||Kinesiology, Health sciences|
|Keywords:||Aerobic Exercise, BDNF, Exercise Science, Kinesiology, Light Therapy, Older Adults|
Copyright in each Dissertation and Thesis is retained by the author. All Rights Reserved
The supplemental file or files you are about to download were provided to ProQuest by the author as part of a
dissertation or thesis. The supplemental files are provided "AS IS" without warranty. ProQuest is not responsible for the
content, format or impact on the supplemental file(s) on our system. in some cases, the file type may be unknown or
may be a .exe file. We recommend caution as you open such files.
Copyright of the original materials contained in the supplemental file is retained by the author and your access to the
supplemental files is subject to the ProQuest Terms and Conditions of use.
Depending on the size of the file(s) you are downloading, the system may take some time to download them. Please be