Guidelines exist for pregnant women to receive the tetanus, diphtheria and pertussis (Tdap) vaccine during weeks 27–36 to protect newborns against pertussis. Despite these guidelines, there is a gap at the clinical site in the uptake of this vaccine in this population. The purpose of this quantitative, quasi-experimental quality improvement (QI) project was to determine if or to what extent the implementation of a health care provider (HCP) educational intervention using current Centers for Disease Control (CDC) vaccine information to strongly recommend the Tdap vaccine to pregnant women would impact the Tdap vaccination rates compared to current practice among pregnant women between 27–36 weeks gestation in an urban prenatal clinic in the Southwestern United States over four weeks. The Plan, Do, Study Act (PDSA) quality improvement model provided a theoretical framework. Data on the CDC vaccine information usage to impact Tdap vaccination rates was measured by Fisher’s exact test. The baseline sample group (no intervention) (n = 22) had 15 out of 22 (68.2%) received the vaccine compared to the post-intervention sample (intervention) (n = 10) had 9 out of 10 (90%) who received the Tdap vaccine. The statistical results were not considered statistically significant (p = .38). However, there is clinical significance in the increased number of vaccines given after implementation. The results indicated the intervention may increase the Tdap vaccination rates among the prenatal population. Therefore, the recommendation is to replicate the project over a longer period of time and with a larger sample size to correlate the statistical and clinical significance.