The primary objective of this research study was to explore the influence of leadership style, generational affiliation, and gender on federal employee job satisfaction. This study was performed to determine the statistically significant main effect and interactions between the variables. The design employed was a quantitative, nonexperimental study involving a three-way ANOVA. The independent variables in the study included three types of leadership style (e.g., transformational, transactional, and passive avoidant), three types of generational affiliation (e.g., baby boomer, Generation X, and Generation Y or millennial), and two types of gender (e.g., male and female) resulting in a 3 × 2 × 2 factorial ANOVA. This study was conducted at a headquarters location with a large governmental organization’s employees as the participants, through online questionnaires. The instruments used were the Multifactor Leadership Questionnaire (MLQ) and the Minnesota Satisfaction Questionnaire (MSQ). The literature review indicates the influence of leadership styles, generational affiliation, or gender on employee job satisfaction. However, these studies were predominantly conducted in private and public organizations. Though some studies that were conducted in federal settings explored the influence of leadership style on employee job satisfaction, additional inquiries were needed due to the limitations of the research studies. This research study suggested that leadership style, as most literature studies showed, was statistically significantly influential to federal employee job satisfaction. However, this study also found that neither generational affiliation nor gender was statistically significantly influential to federal employee job satisfaction. Additional findings on this study also showed a positive interaction between leadership style and generational affiliation on federal employee job satisfaction. Though, this study did not further explore any reasons for the interactions but left open many options for further research studies.