Businesses today struggle with financial statement fraud, and financial statement fraud negatively affects the economy. Researchers indicated that financial statement fraud continues to be a problem even though businesses use professional auditors to assess and mitigate the risk of financial statement fraud. This nonexperimental quantitative study with a correlational design used enhanced professional certification as the independent variable, and professional skepticism and risk assessment as the two dependent variables. The study employed random sampling to survey 116 United States’ CPAs via Qualtrics. The research questions were posed to determine the possible relationships between enhanced professional certification and professional skepticism and enhanced professional certification and fraud risk assessment. Finally, the moderating relationship of enhanced professional certification on professional skepticism, and fraud risk assessment was tested. Possible relationships between variables were tested using multiple regression analyses. Data analyses indicated no statistically significant relationship existed between (a) enhanced professional certification and professional skepticism, and (b) enhanced professional certification and fraud risk assessment. Finally, the results revealed enhanced professional certification had no statistically significant moderating effect on the relationship between professional skepticism and fraud risk assessment. Recommendations for future research included replicating the study but increasing the sample size. Future studies should also include factors such as the number of years and level of auditing experience.