Using the Multicultural Model of Stress theoretical framework, the present study compares problem-focused, emotion-focused, and meaning-focused coping mechanisms among Jamaican and American psychology undergraduates. The sample size consisted of 269 (125 Americans and 144 Jamaicans) psychology undergraduates attending the University of West Indies in Kingston, Jamaica and The Chicago School of Professional Psychology. Jamaican and American psychology undergraduates completed the Perceived Stress Scale-10 (Cohen, Kamarck, & Mermelstein, 1983), which identified their perceived stress levels. Additionally, the Coping Across Situations Questionnaire (Seiffge-Krenke, 1955) was completed and used to measure the differing strategies (from 20 alternatives) they usually employed when dealing with a myriad of stressors (covering 8 different domains). Results from findings show that there was minimal difference between the two groups in terms of how they perceived and experienced stress. Both the Jamaican and American psychology undergraduate control groups exhibited similar preferences for utilizing coping mechanisms. However, 50% of aggregate responders indicated the preference for problem-focused coping mechanisms, and 42% stated a preference for meaning-focused strategies with varying stressors. The Jamaican group indicated a slightly higher tendency to rely on emotion-focused strategies than the Americans when it related to dealing with their friends and concerns for their future.