The present study investigated the relationships between academic advising and mental wellness in Thai college students. To better understand Thai students’ mental wellness, depression, anxiety, stress, self-esteem and resiliency were examined. The study intended to find relationships among variables for academic advising helpfulness, GPA, physical activity and mental wellness. A total of 742 undergraduate students ranging in ages from 18-24 were given surveys that contained a demographic questionnaire, Depression Anxiety Stress Scales (DASS-21), Rosenberg Self-esteem Scale (RSE) and Conner-Davidson Resilience Scale (CD-RISC-25). Pearson’s correlation analysis resulted in significant correlations among academic advising helpfulness, GPA, physical activity, resiliency, and mental wellness (depression, anxiety, stress, self-esteem, and resiliency). Student affairs professionals and administrators must understand the factors related to college students' mental wellness in order to identify needs, provide effective programming, and train professional staff to help students cope with stressors throughout their college years.