Dissertation/Thesis Abstract

Deep Learning Applications for Medical Imaging and Time-Series Data
by Martinez, Anthony, M.S., California State University, Long Beach, 2019, 60; 27545665
Abstract (Summary)

With the advent of deep convolutional neural networks, conventional machine learning algorithms have been increasingly displaced, particularly in the computer vision domain. Notably, convolutional neural networks have proven indispensable in image classification, segmentation, and object detection which has driven innovation in self-driving cars, facial recognition, and pedestrian detection to name a few. Similarly, the successful application of DCNNs to medical imaging could expedite experimentation and analysis that may lead to future treatments or contribute to improvements in the standard of care. However, the scarcity and uniqueness of medical imaging pose challenging scenarios that require novel methodologies. Likewise, time-series classification tasks are also hampered by limited and unique data. Still, the application of DCNNs to this task also outperforms conventional methods and demonstrates the flexibility of CNNs in automatically extracting features in various situations. In this thesis, three distinct tasks with limited data are addressed using DCNNs.

First, object localization is applied to a 3 dimensional MRI dataset to facilitate cochleae extraction. Experimental results show that localization is possible within a 1.71 voxel error. Second, this thesis explores CNN architectures for time-series classification of shark behaviors based on data collected by the CSULB Shark Lab. Experimental results show a weighted-average F1-score of 80.0%. Lastly, synaptic cleft segmentation is performed on serial section Transmission Electron Microscopy volumes, where submission to the CREMI challenge ranks 1st on the leaderboard.

Indexing (document details)
Advisor: Zhang, Wenlu
Commitee: Fu, Bo, Kim, Eun Heui
School: California State University, Long Beach
Department: Computer Engineering and Computer Science
School Location: United States -- California
Source: MAI 81/7(E), Masters Abstracts International
Subjects: Computer science, Artificial intelligence
Keywords: Biomedical, Classification, CREMI, Deep learning, Object detection, Segmentation
Publication Number: 27545665
ISBN: 9781392671863
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