Alternate day fasting (ADF) leads to weight loss in humans and rats. To examine the effects of ADF on diet preference, rats were assigned to alternate day or free food access and presented with chow and high-energy (HE) food. Satiety peptides CCK and exendin-4 were administered to determine if they altered the relationship between fasting and preference. Fasting decreased HE preference compared to controls. For males, this was driven by an increase in size and number of chow meals. For females, this was driven by an increase in chow meal number. ADF appeared to increase orosensory stimulation and/or decrease sensitivity to inhibitory cues for males; for females it appeared to decrease sensitivity to inhibitory cues. Peptides did not moderate the relationship between fasting and preference, but exendin-4 decreased HE preference across all groups. Shifts in diet preference may contribute to the effectiveness of using ADF as a dieting strategy.
|Commitee:||Schug, Robert, Zavala, Arturo|
|School:||California State University, Long Beach|
|School Location:||United States -- California|
|Source:||MAI 58/02M(E), Masters Abstracts International|
|Keywords:||Alternate day fasting, Ingestive behavior, Meal pattern analysis, Peptides, Preference, Rats|
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