Dissertation/Thesis Abstract

The author has requested that access to this graduate work be delayed until 2020-08-22. After this date, this graduate work will be available on an open access basis.
Inorganic-Biological Hybrids for Solar-to-Chemical Production
by Sakimoto, Kelsey Kenzo, Ph.D., University of California, Berkeley, 2016, 70; 10189336
Abstract (Summary)

The interplay of chemistry and biology holds many opportunities to address the woes of the modern world. As synthetic chemistry and cell biology have married together to make great strides in health and medicine, an amalgamation of inorganic materials chemistry and microbiology holds similar promise to revolutionize our approach to transducing solar energy into chemical bonds. By combining the superior light harvesting of inorganic semiconductors with enzymatic biocatalysts, high efficiency solar-to-chemical production of complex molecules and materials may outcompete natural photosynthesis. In this work, I describe a series of investigations into the physical and chemical interactions of inorganic-biological hybrid organisms. In the Sporomusa ovata-silicon nanowire system, changes in salt concentrations predictably controlled cell-nanowire alignment, producing a predictive model of inorganic-biological colloidal interaction. The hybrid organism Moorella thermoacetica-cadmium sulfide self-photosensitized the synthesis of acetic acid from CO2 via bioprecipitated CdS nanoparticles. A titanium dioxide-manganese(II) phthalocyanine photocatalyst system extended oxygenic photosynthesis in M. thermoacetica -CdS through a photoregenerative cysteine-cystine redox couple. Finally, transient absorption spectroscopy, time-resolved infrared spectroscopy and biochemical assays suggested a two-pathway mechanism of charge and energy transport between M. thermoacetica and CdS. These initial works at the nexus of materials chemistry and biology lay the foundation for deeper understanding of this complex interface as well as for the development of advanced solar-to-chemical production systems.

Indexing (document details)
Advisor: Yang, Peidong
Commitee: Chang, Michelle CY, Lee, Luke P., Xu, Ke
School: University of California, Berkeley
Department: Chemistry
School Location: United States -- California
Source: DAI-B 80/01(E), Dissertation Abstracts International
Subjects: Microbiology, Chemistry, Materials science
Keywords: Acetogen, Carbon dioxide, Chalcogenide, Nanoscience, Photocatalysis, Photosynthesis
Publication Number: 10189336
ISBN: 9780438347137
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