Nurses can experience stress and perceived traumatic events during their career. This distress in the workplace can affect the quality of life of nurses. Exposure to perceived distressing events may lead to burnout, compassion fatigue, post-traumatic stress disorder, patient errors or poor outcomes, horizontal violence or even nurses leaving the profession. Peer support is a strategy which has been explored to increase defensive lines and improve coping. The purpose of this descriptive, correlational study was to examine if a relationship exists between the use of peer support, as conceptualized within the framework of the Neuman System Model, and the quality of life with participating nurses. It was hypothesized that a relationship exists between peer support and the quality of life of nurses. The data analyzed from the completed surveys of the 140 participating nurses demonstrated that there were statistically significant relationships between peer support, captured through use of the PRQ 2000, and the quality of life, as operationalized through the ProQOL. There was a strong positive correlation between perceived peer support and compassion satisfaction (r = .808, p = 0.000), a strong negative correlation between perceived peer support and burnout (r = -.835, p = 0.000), and a moderate negative correlation between perceived peer support and secondary traumatic stress (r = -.324, p = 0.000). This study adds to the body of evidence regarding the quality of life of nurses who experience workplace stress, and the potential for peer support to be used as a strategy.