Dissertation/Thesis Abstract

Neuromuskuläres Assessment durch Bodenreaktionskraftanalysen im Rahmen der Sarkopeniediagnostik bei älteren Männern
by Lieberoth-Leden, Dominik, Ph.D., Bayerische Julius-Maximilians-Universitaet Wuerzburg (Germany), 2018, 187; 10971506
Abstract (Summary)

The following research paper addresses the clinical application and validation of ground reaction force analysis as neuromuscular assessment in old aged men for more precise quantification of neuromuscular power especially concerning the diagnostic of sarcopenia. Therefore, a cohort of over 500 old aged men between the age of 65 and 90 years of age were recruited in a community dwelling population of different districts in the city of Würzburg, Germany. There were only a few exclusion criteria applied to avoid exclusion of multimorbid and mobility limited participants. Concerning the analysed ground reaction force measurements of successfully conducted single two leg jumps in 457 old aged men there was a highly significant linear descent in jump power, -velocity and -height with age whereas almost no decline in jump force detected. There was no difference in proportionality or slope of decline compared to results of jumping mechanography compared to existing reference data of analysed healthy and relatively fit old aged. Nevertheless, there was an absolute and obvious deficiency exposed. Concerning anthropometric measurements of the cohort there was a negative impact of BMI, sceletal muscle mass (SM) and sceletal muscle mass index (SMI) on parameters of jumping mechanography. With decreasing jump power over age there was an overproportioned decrease in jump velocity compared to jump force, both multiplied resulting in jump power. Sarcopenic participants demonstrated significantly lower jump power than non Sarcopenic even though the vast majority of patients had been declared sarcopenic, according to the postulated algorithm of the EWGSOP, through the combination of decreased muscle mass and grip strength. Regular physical activity in old aged as well as sarcopenic and non sarcopenic patients seems to have positive impact on jump power. Almost all observations confirm the thesis of the importance of decline in muscle quality over -quantity. There are more and longitudinal studies needed as well as greater cohorts of sarcopenic patients to confirm the results in different populations and concerning the potential decline in contraction velocity of the muscle as a potential an promising approach for therapy and in intervention ass well as regular physical exercise in old aged.

Indexing (document details)
Advisor: Jakob, Franz, Jakubietz, Michael
Commitee:
School: Bayerische Julius-Maximilians-Universitaet Wuerzburg (Germany)
School Location: Germany
Source: DAI-C 81/1(E), Dissertation Abstracts International
Source Type: DISSERTATION
Subjects: Neurosciences
Keywords: Ground reaction force analysis
Publication Number: 10971506
ISBN: 9781392524848
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