Dissertation/Thesis Abstract

Phase 3 Study Site Location and African American Access to Clinical Trials
by Markmann, Joseph W., Ph.D., University of the Sciences in Philadelphia, 2018, 218; 10904833
Abstract (Summary)

By nearly every measure, the African American community has poorer health outcomes and greater costs to treat the afflictions that they are burdened with. In many ways, these issues are rooted in decreased access to care in comparison to the white population. However, the health issues faced by the black population may also stem from the fact that the drugs that they use to treat their diseases don’t work because they are not part of the process to develop them.

Two hypotheses prevail in the literature about why black people do not participate in clinical trials. Issues stemming from a history of abuse and racial discordance between black patients and white physicians underlie the mistrust of the healthcare system hypothesis. The second focuses on limited access and addresses whether black patients are even asked to participate. Building on the access theme, this research addresses whether clinical studies are conducted where black people live.

This research assesses black access to clinical trials by measuring whether clinical trial sites are located in areas proximal to where black people live. This analysis is conducted by comparing the regional black population percentage surrounding clinical trial sites to the national proportion. This analysis will be conducted for all Phase 3 clinical studies conducted in the US, and then specifically for Type II Diabetes studies, as this is a disease that disproportionately impacts the black community.

Indexing (document details)
School: University of the Sciences in Philadelphia
Department: Health Policy and Public Health
School Location: United States -- Pennsylvania
Source: DAI-B 79/12(E), Dissertation Abstracts International
Subjects: Health sciences
Keywords: Clinical trial access, Clinical trial segregation, Health policy, Healthcare access, Healthcare segregation, Minority health
Publication Number: 10904833
ISBN: 9780438157378
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