This study examined the association between chronic residential exposure to low-level ionizing radiation and risk of leukemia and non-Hodgkin's lymphoma (NHL). Subjects included 8,220 people living within a five-mile radius of a uranium processing plant in Fernald, Ohio. A retrospective cohort design was used, including incident cases of leukemia and NHL that developed after 1990. Estimates of radiation exposure were based on subjects' location and duration of residence. Logistic regression and Cox proportional hazards regression were used to determine if there was an association between level of radiation exposure and risk of leukemia and NHL, controlling for age. Other covariates included gender, SES, smoking status, X-ray history, family history of cancer, and exposure to benzene, asbestos, or farming. Results indicated a non-significantly elevated OR for radiation exposure among the leukemia cohort. For the NHL cohort, there was no clear association between radiation exposure and risk of disease.
|School:||University of Cincinnati|
|Department:||Medicine : Epidemiology|
|School Location:||United States -- Ohio|
|Source:||MAI 57/06M(E), Masters Abstracts International|
|Keywords:||Exposure assessment, Leukemia, Non-hodgkin's lymphoma, Radiation|
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