Dissertation/Thesis Abstract

Vagus Nerve Stimulation Therapy for Intractable Epilepsy: A Patient's Perspective
by Cuthbertson, Mark, M.L.S., The University of Toledo, 2006, 64; 10836006
Abstract (Summary)

This study documents the journey of one intractable Epilepsy patient contemplating the implantation of a Vagus Nerve Stimulation (VNS) device. Intractable, or pharmacoresistant, Epilepsy is Epilepsy that is uncontrolled despite appropriate medical treatment with antiepileptic drugs (AED's). More than 30% of patients continue to have seizures in spite of multiple trials with pharmacologic therapy (Kwan & Brodie 2000).

Scientists had long known that electrical stimulation of the vagus nerve in the neck could “flatten out” brain waves, thus possibly decreasing seizure activity, and in 1997, the U.S. Food and Drug Administration (FDA) approved VNS Therapy in combination with seizure medication. On the surface, it might appear that the decision would be an easy one, yet past frustrations and the uncertainty of favorable results make this decision one worth studying.

Indexing (document details)
Advisor: Sherry, Mark
School: The University of Toledo
Department: Arts and Sciences
School Location: United States -- Ohio
Source: MAI 57/06M(E), Masters Abstracts International
Subjects: Medicine
Keywords: Intractable epilepsy, Seizures, Vagus nerve, Vns
Publication Number: 10836006
ISBN: 978-0-355-97190-3
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