The central focus of the study was to quantify, under precisely controlled metabolic balance condition, the increase in fecal excretion of dietary phosphorus that occurs when CPD patients ingest lanthanum carbonate. The dose response relationship between lanthanum carbonate treatment and fecal phosphorus excretion under constant phosphorus intake condition was determined. Suggesting that doses between 3.0 grams of lanthanum carbonate per day and 4.5 grams are optimal for all the patients participated in the study. Finally the body phosphorus balance was calculated under each of the lanthanum carbonate doses and was determined to be negative for all the patients under 4.5 g/day or lanthanum carbonate.
|Commitee:||Kopple, Joel, Slowinska, Katarzyna|
|School:||California State University, Long Beach|
|Department:||Chemistry and Biochemistry|
|School Location:||United States -- California|
|Source:||MAI 57/01M(E), Masters Abstracts International|
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