In the study of visual function an understanding of the visual pathways is essential. Once this is achieved then quantitative measurements can be made in order to assess the quality of vision. However, this development can at times be problematic and may lead to visual disorders. Some of these visual disorders are directly related to the development but others may not. We are concerned with mainly one of these visual disorders, infantile nystagmus syndrome (INS). Common ways INS is assessed is through visual evoked potentials (VEP), or electroretinigrams (ERG). The current work is a comprehensive multidisciplinary attempt to develop new tools and methods for assessing these visual functions in order to both complement as well as introduce new clinical tools that will help in finding efficient treatments by identifying the activation patterns in the brain. This is divided into three stages: functional magnetic resonance imaging (FMRI) of oculomotor movements, development of a near infrared spectroscopy system (NIRS) for visual cortex monitoring, and finally an MRI post processing scheme to enhance the cortical imaging. These three stages are an attempt to develop tools in order to aid in visual function studies.
|Advisor:||Roberts, Cynthia J.|
|Commitee:||Leguire, Lawrence E., Roberts, Cynthia J., Xu, Ronald X.|
|School:||The Ohio State University|
|School Location:||United States -- Ohio|
|Source:||DAI-B 78/11(E), Dissertation Abstracts International|
|Subjects:||Ophthalmology, Biomedical engineering|
|Keywords:||Functional studies, Methods, Visual function|
Copyright in each Dissertation and Thesis is retained by the author. All Rights Reserved
The supplemental file or files you are about to download were provided to ProQuest by the author as part of a
dissertation or thesis. The supplemental files are provided "AS IS" without warranty. ProQuest is not responsible for the
content, format or impact on the supplemental file(s) on our system. in some cases, the file type may be unknown or
may be a .exe file. We recommend caution as you open such files.
Copyright of the original materials contained in the supplemental file is retained by the author and your access to the
supplemental files is subject to the ProQuest Terms and Conditions of use.
Depending on the size of the file(s) you are downloading, the system may take some time to download them. Please be