The use of global positioning systems (GPS) is the new standard in applied sports science research. In order to overcome limitations of GPS technology, Catapult Sports has combined accelerometer and gyroscope information to create a non-gravity vector, which allows teams to utilize Inertial Movement Analysis (IMA) indoors and outdoors using an athlete-based coordinate system. This study examined the individual correlations between IMA accelerations, decelerations, player load, position, time in season and training day in 23 Major League Soccer players who are full time professionals and play for the same club. Strong associations were found between total player load, total high IMA, IMA acceleration high, and IMA deceleration high, with very strong correlation between total high IMA and IMA deceleration high. Three days before game day (GD-3) has higher, on average, IMA counts and total player load in the training week, regardless of player position, as opposed to the hypothesized four days before game day (GD-4). It is important to include IMA levels along with player load in a periodization program in order to maximize the player’s potential and performance.