Dissertation/Thesis Abstract

Pharmacogenomics information-seeking behavior and the openinfobutton solution
by Heale, Bret Scot Edward, M.S., The University of Utah, 2016, 83; 10248942
Abstract (Summary)

Lack of information is a serious concern for clinicians. Information resources can address this problem, leading to improvements in decision making and patient outcomes. Genomics is an information-rich domain where searching for information can be complex. For example, most physicians agree that pharmacogenomics can be used to improve the quality of care, and there is evidence that many patients harbor actionable pharmacogenomic variation. However, surveys have shown that physicians feel their knowledge of pharmacogenomics to be inadequate. This represents an information need. A natural approach to meet this need is to provide context-aware access to the precise information needed. The Health Level 7 Context-Aware Knowledge Retrieval Standard, a.k.a the Infobutton, offers a modality to deliver context-aware knowledge into electronic health record (EHR) systems. OpenInfobutton is a reference implementation of this standard that offers an open-source instantiation. In this thesis, we aimed to provide insight into pharmacogenomics information needs and an automated mechanism for addressing these needs. Such work can aid the design of tools that support clinical decisions in genomics.

Indexing (document details)
Advisor: Del Fiol, Guilherme
Commitee: Jackson, Brian R., Luo, Gang
School: The University of Utah
Department: Biomedical Informatics
School Location: United States -- Utah
Source: MAI 56/03M(E), Masters Abstracts International
Subjects: Genetics, Information Technology, Medicine
Keywords: HL7, Healthcare IT, Infobutton - clinical decision support, Information seeking behavior, Pharmacogenomics, Standards
Publication Number: 10248942
ISBN: 9781369595574
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