Dissertation/Thesis Abstract

The Effect of Medicinal Plants Fennel Seeds, and Olive Leaves to Inhibit Growth on Lung, Leukemia, and Colon Cell Lines
by Alalyu, Ruqayyah Saeed, M.S., Tennessee State University, 2016, 51; 10158637
Abstract (Summary)

Cancer is a deadly disease has no respect for age and sex, but it can affect any person at any time. Cancer is a serious health problem and the second leading cause of death in the United States and many other parts of the world. Cancer is a named for a disease in which abnormal cells grow out of control and ability to invade other tissues. Cancer cells can spread from the initial mutation site to other areas of the body. Scientists defined Cancer as a complex group of diseases. Cancer researchers found that there were more than 100 types of cancers. Plants have been proved to be an important natural source of anti-cancer compounds for several years.

In the last two decades, we were becoming increasingly more aware of this disease, so we start making progress in the treatment from Natural product sources such as plants to attack the growing issue of cancer. Olive Leaves (Olea European L.), and Fennel Seed (Foeniculum vulgare) were used in this study to determine their effect on three cancer cell lines which are HL60, A549, and SW620. The experiment duration was 24 hours, and the results were obtained, recorded, and analyzed. The Growth analysis was determined using a cell viability indicator Alamar blue and a fluorescent plate reader. The extracted Olive Leave was found significantly decreased the growth rate and cell subsistence of HL60, A549, and SW620 cancer cell lines at all concentrations. Fennel is traditionally used in the treatment of cancer. Our results show that Fennel inhibits the growth of Lung (A549) cancer cells, and Colon (SW620) cancer cell line.

Indexing (document details)
Advisor: Myles, E. Lewis
Commitee: Boadi, William Y., Guha, Sujata, Johnson, Terrance L.
School: Tennessee State University
Department: Chemistry
School Location: United States -- Tennessee
Source: MAI 55/06M(E), Masters Abstracts International
Subjects: Cellular biology
Keywords: Colon, Fennel, Inhibit, Leaves, Leukemia, Lung, Medicinal, Olive, Plants, Seeds
Publication Number: 10158637
ISBN: 9781369136456
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