Dissertation/Thesis Abstract

Turbulent simulations of feline aortic flow under hypertrophic cardiomyopathy heart condition
by Borse, Manish Rajendra, M.S., Mississippi State University, 2016, 106; 10141653
Abstract (Summary)

A computational fluid dynamics (CFD) model is developed for pulsatile flows and particle transport to evaluate the possible thrombus trajectory in the feline aorta for Hypertrophic Cardiomyopathy (HCM) heart conditions. An iterative target mass flow rate boundary condition is developed, and turbulent simulations with Lagrangian particle transport model are performed using up to 11M grids. The model is validated for human abdominal aorta flow, for which the results agree within 11.6% of the experimental data. The model is applied for flow predictions in a generalized feline aorta for healthy and HCM heart conditions. Results show that in the HCM case, the flow through the iliac arteries decreases by 50%, due to the large recirculation regions in the abdominal aorta compared to the healthy heart case. The flow recirculation also result in stronger vortices with slower decay, causing entrapment of particles in the thoracic aorta and trifurcation regions.

Indexing (document details)
Advisor: Bhushan, Shanti
Commitee: Burgreen, Greg W., Chen, Lei, Walters, Keith D.
School: Mississippi State University
Department: Mechanical Engineering
School Location: United States -- Mississippi
Source: MAI 55/06M(E), Masters Abstracts International
Source Type: DISSERTATION
Subjects: Mechanical engineering
Keywords: Computational fluid dynamics, Feline aorta, Hypertrophic cardiomyopathy, Particle transport, Pulsatile flow, Thromboembolism
Publication Number: 10141653
ISBN: 9781339970134
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