A computational fluid dynamics (CFD) model is developed for pulsatile flows and particle transport to evaluate the possible thrombus trajectory in the feline aorta for Hypertrophic Cardiomyopathy (HCM) heart conditions. An iterative target mass flow rate boundary condition is developed, and turbulent simulations with Lagrangian particle transport model are performed using up to 11M grids. The model is validated for human abdominal aorta flow, for which the results agree within 11.6% of the experimental data. The model is applied for flow predictions in a generalized feline aorta for healthy and HCM heart conditions. Results show that in the HCM case, the flow through the iliac arteries decreases by 50%, due to the large recirculation regions in the abdominal aorta compared to the healthy heart case. The flow recirculation also result in stronger vortices with slower decay, causing entrapment of particles in the thoracic aorta and trifurcation regions.
|Commitee:||Burgreen, Greg W., Chen, Lei, Walters, Keith D.|
|School:||Mississippi State University|
|School Location:||United States -- Mississippi|
|Source:||MAI 55/06M(E), Masters Abstracts International|
|Keywords:||Computational fluid dynamics, Feline aorta, Hypertrophic cardiomyopathy, Particle transport, Pulsatile flow, Thromboembolism|
Copyright in each Dissertation and Thesis is retained by the author. All Rights Reserved
The supplemental file or files you are about to download were provided to ProQuest by the author as part of a
dissertation or thesis. The supplemental files are provided "AS IS" without warranty. ProQuest is not responsible for the
content, format or impact on the supplemental file(s) on our system. in some cases, the file type may be unknown or
may be a .exe file. We recommend caution as you open such files.
Copyright of the original materials contained in the supplemental file is retained by the author and your access to the
supplemental files is subject to the ProQuest Terms and Conditions of use.
Depending on the size of the file(s) you are downloading, the system may take some time to download them. Please be