Alternative saline therapies are one way to provide supplemental treatment to patients with Cystic Fibrosis (CF); surfing represents one form of therapy that may increase health-related quality of life (HRQoL). To date, however, many assumptions about surfing’s effectiveness are based only on trials with hypertonic saline solution (extra salty sterile water), thus warranting the need to test effectiveness with a group of CF patients who use surfing as part of their treatment. The purpose of this study was to evaluate the impact of Surf Experience Days (SEDs) on the HRQoL of participating youth; the secondary goal was to assess the presence of a dose-response relationship. Findings suggest indicators of HRQoL amongst youth with CF improved due to participation in the Mauli Ola Foundation (MOF) SED’s. Greater frequency of participation in MOF SED’s was not associated with greater improvements in HRQoL. Future studies with larger samples and additional measures are recommended