Nonadherence to antihypertensive medications is a widespread problem among dialysis patients. Nonadherence to antihypertensive medications can result in the dialysis patients’ morbidity and mortality. A pilot study was used to determine whether a medication reminder mobile application would improve dialysis participants’ adherence to their prescribed antihypertensive medications from a Midwest outpatient dialysis clinic. Dialysis participants prescribed one or more antihypertensive medications were invited to participate in the pilot study using Dosecast®, a mobile medication reminder application. The dialysis participants completed four self-reported questionnaires: Demographic Questionnaire, Brief Medication Questionnaire (BMQ-1), Modified Patient Satisfaction with Nursing Care Quality Questionnaire (PSNCQQ), and Morisky Medication Adherence Questionnaire (MMAS-8). The questionnaires were analyzed with descriptive statistics and an independent t-test. The results from the 20 dialysis participants showed that the participants’ improved their adherence with the antihypertensive medications. This showed that Dosecast® is a beneficial tool to increase dialysis participants’ adherence to antihypertensive medications.