PURPOSE: The purpose of this study was to determine if surgically-induced menopause in younger women affects substrate utilization during submaximal exercise while controlling for other potential confounds. METHODS: Thirteen untrained female subjects (33-50 years old) were recruited: oophorectomized (Group O = 5) and premenopausal controls (Group C = 8). Two separate visits included: body composition and maximal treadmill exercise test; followed by substrate utilization via open-circuit spirometry during 45 minutes of treadmill walking at 50% VO2max. RESULTS: When controlling for multiple variables affecting whole-body substrate utilization (age, VO2max, physical activity, body composition, fasting glucose, menstrual phase and diet), there was no difference in substrate utilization between pre- and postmenopausal women as measured by respiratory exchange ratio (RER) (0.83 ± 0.04 v 0.84 ± 0.03, p=0.47). CONCLUSIONS: Menopausal status does not appear to have an effect on substrate utilization during submaximal exercise in younger women.
|School:||Florida Atlantic University|
|School Location:||United States -- Florida|
|Source:||MAI 55/04M(E), Masters Abstracts International|
|Keywords:||Exercise, Menopause, Metabolism, Oophorectomy, Previvors, Substrate utilization|
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