Dissertation/Thesis Abstract

The relationship between folic acid, vitamin B12, and vitamin B6 intakes and depression in women who use hormonal oral contraceptives
by Zolfaghari, Sara S., M.S./M.P.H., California State University, Long Beach, 2015, 109; 1604887
Abstract (Summary)

Depression is a leading cause of disability and mortality worldwide, especially for women. No nutrition recommendations exist for depression. Oral contraceptives (OCs) have become the leading form of pregnancy prevention in the United States. Studies have associated OC use with impaired nutrient status, specifically folate, vitamin B12, and vitamin B6, which also affect brain functions. Dietary folate, vitamin B12, and vitamin B6 self-reported intakes were used to determine the relationship between depression in women who used OCs (n = 34) in a selected cohort ( n = 409) from the National Health and Nutrition Examination Survey, 2003–2008. OC users were more depressed than non-OC users; depression was associated with various quartile levels of vitamin intake (p <.001). No benefit was observed with intakes which exceeded RDAs for non-OC users; OC users were less depressed when intakes exceeded RDAs for folate, vitamin B12, and vitamin B6 by 13%, 75%, and 7%, respectively.

Indexing (document details)
Advisor: Wang, Long
Commitee: Gray, Virginia, Roy, Roudi
School: California State University, Long Beach
Department: Family and Consumer Sciences
School Location: United States -- California
Source: MAI 55/02M(E), Masters Abstracts International
Source Type: DISSERTATION
Subjects: Mental health, Nutrition
Keywords: Depression, NHANES, Oral contraceptives, Vitamin
Publication Number: 1604887
ISBN: 9781339292977
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