From the perspective of acculturation stress theory, the historical background of Iranian immigrants is visited in this dissertation, as well as different types of acculturation strategies that are being utilized by immigrants. This research study addresses the impacts of inadequate access to and underutilization of mental health services on the psychosocial wellbeing of Iranian families, and the lack of appropriate interventions due to ongoing stress, such as economic hardships. Furthermore, the usefulness of several inexpensive and accessible stress-reduction techniques in reestablishing psychophysiological relaxation is examined. It is noted that, in spite of their long history, such techniques are not widely recognized as effective coping skills in response to stress-inducing immigration experiences. In addition, the relaxation qualities of music are reviewed, revealing consistent therapeutic effects and significant relaxation responses elicited in the listeners. The purpose of this applied research study was to develop a proposed Hindustani music-assisted multimodal guided relaxation intervention designed to lower stress and particularly, acculturation stress experienced by Iranian families. An evaluation of the program's efficacy by validity judges concluded that this program is potentially effective for inducing relaxation responses in the listeners.