As organizations become increasingly complex, research into the sources and effects of employee stress is increasingly warranted. The present study examined the relationship between personal life stress, work stress, and job performance. In addition, the role of conscientiousness as a possible moderating variable was analyzed. Several studies regarding the relationship between stress and work performance were reviewed. In the present study, participants completed measures of life stress, job stress, and personality. Supervisors rated the job performance of participants. A significant relationship was found between personal life stress and job stress such that each type of stress was higher when the other was present. Neither personal life stress nor job stress were related to job performance. Conscientiousness was not found to moderate the stress-job performance relationships. Implications of the study and future directions are explored.