Lowered motivation can influence the involvement of adults with brain injury in the rehabilitation process, ultimately affecting the extent of their progress. This within-subject, pretest/posttest design examined the effects of an education program focusing on concepts of neuroplasticity on 34 adults with brain injury. Quantitative data was taken from pre-presentation and post-presentation surveys and was analyzed for significant change. Results indicated that the presentation was successful in increasing (a) the knowledge of neuroplasticity as evidenced by significant change in two out of three items, and (b) level of motivation as evidenced by significant change in six out of nine items. Effects of age, education level, and time post-injury were discussed. Study conclusions validate the use of education to increase motivation in people with brain injury, and provides new information about the use of neuroplasticity in education.