The purpose of this study was to examine the demographic differences in methamphetamine usage among youth and how methamphetamine users engaged in the use of other illegal drugs including, marijuana, cocaine, heroin, ecstasy and also engage in risk taking behaviors. The study utilized secondary data from the National Institute of Health, Youth Behavioral Risk Survey (YRBS) of20011. Sample size consisted of 294 both male and female youth who are methamphetamine users. The findings revealed that drug use amongst youth continues to be on the rise. Findings noted that male meth users had the highest rates of cocaine, ecstasy and heroin use compared to female meth users. The highest rate among female meth users was seen in cocaine use. Findings also revealed that cocaine use was the highest among Hispanic/Latino meth users and ecstasy use was the highest among Non-Hispanic/Latino meth users. In addition findings revealed that a significant association was found in youth's drug use and their involvement in risk taking behaviors. Prior research and findings from this study help society have a more proactive approach when helping youth who suffer from the disease of addiction.