Dissertation/Thesis Abstract

Quantum Tunneling in Hydride Transfer Reactions in Solution
by Razzaghi, Mortezaali, M.S., Southern Illinois University at Edwardsville, 2013, 61; 1549836
Abstract (Summary)

The secondary kinetic isotope effects for the hydride transfer reactions from aliphatic alcohols to four carbocations (NAD+ models) in acetonitrile were determined. The results suggest that the hydride transfer takes place by tunneling and that the rehybridizations of both donor and acceptor carbons lag behind the H-tunneling. This is quite contrary to the observations in alcohol dehydrogenases where the importance of enzyme motions in catalysis is manifested.

Indexing (document details)
Advisor: Lu, Yun
Commitee: Luesse, Sarah, Wei, Chin-Chuan
School: Southern Illinois University at Edwardsville
Department: Chemistry
School Location: United States -- Illinois
Source: MAI 52/04M(E), Masters Abstracts International
Subjects: Organic chemistry, Physical chemistry
Keywords: Alcohol dehydrogenase, Hydride transfer reactions, Kinetic isotope effect, Quantom tunneling effect
Publication Number: 1549836
ISBN: 9781303629112
Copyright © 2019 ProQuest LLC. All rights reserved. Terms and Conditions Privacy Policy Cookie Policy