Dissertation/Thesis Abstract

A partial skeletal proteome of the brittle star Ophiocoma wendtii
by Seaver, Ryan W., M.S., California State University, Long Beach, 2013, 98; 1522653
Abstract (Summary)

The formation of mineralized tissue was critical to the evolution and diversification of metazoans and remains functionally significant in most animal lineages. Of special importance is the protein found occluded within the mineral matrix, which facilitates the process of biomineralization and modulates the final mineral structure. These skeletal matrix proteins have well been described in several species, including the sea urchin Stronglyocentrotus purpuratus, an important model organism. Biomineralization research is limited in other echinoderm classes. This research encompasses the first description of mineral matrix proteins in a member of the echinoderm class Ophiuroidea. This work describes the skeletal matrix proteins of the brittle star Ophiocoma wendtii using bioinformatic and proteomic techniques. General characteristics of matrix protein are described and a number of candidate biomineralization related genes have been identified, cloned, and sequenced. The unique evolutionary and biochemical properties of brittle star skeletal matrix proteins are also described.

Indexing (document details)
Advisor: Livingston, Brian
Commitee: Acey, Roger A., Carter, Ashley J. R.
School: California State University, Long Beach
Department: Biological Sciences
School Location: United States -- California
Source: MAI 51/05M(E), Masters Abstracts International
Subjects: Genetics, Evolution and Development, Atmospheric sciences
Publication Number: 1522653
ISBN: 978-1-303-02065-0
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